Desdemona Fricker

Birthdate: 1969

Birthplace: Augsburg

•2000: Ph.D. thesis in “Pharmacologie Moléculaire et Cellulaire”, Université Pierre et Marie Curie, Paris. «Factors controlling nerve cell excitability in the hippocampus»

•1995: Medical state examination and medical thesis, M.D., Universität Tübingen (Germany)

•1993: Magistère interuniversitaire de Biologie-Biochimie, Ecole Normale Supérieure (ENS), Paris

•1988: Graduation from high school, Gymnasium Mengen (Germany)

•2002-present INSERM U739 Cortex & Epilepsie, Paris, France, Researcher at the Centre National de Recherche Scientifique (CNRS) Activity dependent modifications of intrinsic excitability

•2000-2002 Division of Neuroscience, Baylor College of Medicine, Houston, Texas, USA Research Associate in Dr. Daniel Johnstons laboratory, Long term potentiation (LTP) and cellular plasticity

•1996-2000: Institut Pasteur, Paris, PhD thesis under the direction of Dr. Richard Miles. Factors controlling excitability in hippocampal neurons.

•1995-1996: Lab. de Neurobiologie Cellulaire, Institut des Neurosciences, Paris, PhD thesis, Molecular and Cellular Pharmacology, Presynaptic GABAB receptors on inhibitory afferences in the thalamus.

•1992-1993: Lab. Neurobiologie, Ecole Normale Supérieure ENS, Paris, Medical thesis, under the direction of Prof. Philip Ascher. Structure-function analysis of mutated NMDA receptor channels expressed in Xenopus Oocytes.

Activity-dependent decrease of excitability in rat hippocampal neurons through increases in I(h). Fan Y, Fricker D, Brager DH, Chen X, Lu HC, Chitwood RA, Johnston D. Nat Neurosci. 2005 Nov;8(11):1542-51. Epub 2005 Oct 23. Erratum in: Nat Neurosci. 2006 Jan;9(1):147. PMID: 16234810 [reprint]

The birth (and adolescence) of LTP. Miles R, Poncer JC, Fricker D, Leinekugel X. J Physiol. 2005 Oct 1;568(Pt 1):1-2. Epub 2005 Jul 14. PMID: 16020452 [reprint]

Interneuron Diversity series: Fast in, fast out--temporal and spatial signal processing in hippocampal interneurons. Jonas P, Bischofberger J, Fricker D, Miles R. Trends Neurosci. 2004 Jan;27(1):30-40. Review. PMID: 14698608 [reprint]

Interneurons, spike timing, and perception. Fricker D, Miles R. Neuron. 2001 Dec 6;32(5):771-4. Review. PMID: 11738024 [reprint]

EPSP amplification and the precision of spike timing in hippocampal neurons. Fricker D, Miles R. Neuron. 2000 Nov;28(2):559-69. PMID: 11144364 [reprint]

Cell-attached measurements of the firing threshold of rat hippocampal neurones. Fricker D, Verheugen JA, Miles R. J Physiol. 1999 Jun 15;517 ( Pt 3):791-804. PMID: 10358119 [reprint]

Noninvasive measurements of the membrane potential and GABAergic action in hippocampal interneurons. Verheugen JA, Fricker D, Miles R. J Neurosci. 1999 Apr 1;19(7):2546-55. PMID: 10087068 [reprint]

GABAA receptor-mediated IPSCs in rat thalamic sensory nuclei: patterns of discharge and tonic modulation by GABAB autoreceptors. LeFeuvre Y, Fricker D and Leresche N. Journal of Physiology (Lond.) 1997 502, 91-104 PMID: 9234199 [reprint]

Differences in the temporal precision of EPSP - Spike coupling at synapses that excite hippocampal inhibitory and pyramidal cells. Miles R and Fricker D. European Journal of Neuroscience 2000 12 : S 311-311.